Hypotheses in Marketing Science: Literature Review and Publication Audit

We examined three approaches to research in marketing: exploratory hypotheses, dominant hypothesis, and competing hypotheses. Our review of empirical studies on scientific methodology suggests that the use of a single dominant hypothesis lacks objectivity relative to the use of exploratory and competing hypotheses approaches. We then conducted a publication audit of over 1,700 empirical papers in six leading marketing journals during 1984-1999. Of these, 74% used the dominant hypothesis approach, while 13 % used multiple competing hypotheses, and 13% were exploratory. Competing hypotheses were more commonly used for studying methods (25%) than models (17%) and phenomena (7%). Changes in the approach to hypotheses since 1984 have been modest; there was a slight decrease in the percentage of competing hypotheses to 11%, which is plained primarily by an increasing proportion of papers on phenomena. Of the studies based on hypothesis testing, only 11 % described the conditions under which the hypotheses would apply, and dominant hypotheses were below competing hypotheses in this regard. Marketing scientists differed substantially in their opinions about what types of studies should be published and what was published. On average, they did not think dominant hypotheses should be used as often as they were, and they underestimated their use

Hypotheses in Marketing Science: Literature Review and Publication Audit

We examined three approaches to research in marketing: exploratory hypotheses, dominant hypothesis, and competing hypotheses. Our review of empirical studies on scientific methodology suggests that the use of a single dominant hypothesis lacks objectivity relative to the use of exploratory and competing hypotheses approaches. We then conducted a publication audit of over 1,700 empirical papers in six leading marketing journals during 1984-1999. Of these, 74% used the dominant hypothesis approach, while 13 % used multiple competing hypotheses, and 13% were exploratory. Competing hypotheses were more commonly used for studying methods (25%) than models (17%) and phenomena (7%). Changes in the approach to hypotheses since 1984 have been modest; there was a slight decrease in the percentage of competing hypotheses to 11%, which is explained primarily by an increasing proportion of papers on phenomena. Of the studies based on hypothesis testing, only 11 % described the conditions under which the hypotheses would apply, and dominant hypotheses were below competing hypotheses in this regard. Marketing scientists differed substantially in their opinions about what types of studies should be published and what was published. On average, they did not think dominant hypotheses should be used as often as they were, and they underestimated their use.marketing, marketing research, marketing science

The future of robotic surgery

© 2018 Royal College of Surgeons.For 20 years Intuitive Surgical’s da Vinci® system has held the monopoly in minimally invasive robotic surgery. Restrictive patenting, a well-developed marketing strategy and a high-quality product have protected the company’s leading market share.1 However, owing to the nuances of US patenting law, many of Intuitive Surgical’s earliest patents will be expiring in the next couple of years. With such a shift in backdrop, many of Intuitive Surgical’s competitors (from medical and industrial robotic backgrounds) have initiated robotic programmes – some of which are available for clinical use now. The next section of the review will focus on new and developing robotic systems in the field of minimally invasive surgery (Table 1), single-site surgery (Table 2), natural orifice transluminal endoscopic surgery (NOTES) and non-minimally invasive robotic systems (Table 3).Peer reviewedFinal Published versio

Review of the evidence for robotic-assisted robotic cystectomy and intra-corporeal urinary diversion in bladder cancer

Funding Information: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi. org/10.21037/tau.2019.12.19). The series “Muscle-Invasive Bladder Cancer” was commissioned by the editorial office without any funding or sponsorship. Dr. Decaestecker reports personal fees and non-financial support from Intuitive Surgical, personal fees and non financial support Publisher Copyright: © Translational Andrology and Urology. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Radical cystectomy, pelvic lymph node dissection and urinary diversion is the gold-standard treatment for muscle-invasive bladder cancer. The surgery is both complex and highly morbid. Robotic cystectomy is now in its 16th year with established techniques and sufficient research maturity to enable comparison with its open counterpart. The present review focuses on the current evidence for robotic cystectomy and assesses various metrics including oncological, perioperative, functional, surgeon-specific and cost outcomes. The review also encapsulates the current evidence for intra-corporeal urinary diversion and its current status in the cystectomy arena.Peer reviewe

Deep Chandra Monitoring Observations of NGC 4649: II. Wide-Field Hubble Space Telescope Imaging of the Globular Clusters

We present g and z photometry and size estimates for globular clusters (GCs) in the massive Virgo elliptical NGC 4649 (M60) using a five-pointing Hubble Space Telescope/Advanced Camera for Surveys mosaic. The metal-poor GCs show a monotonic negative metallicity gradient of (-0.43 +/- 0.10) dex per dex in radius over the full radial range of the data, out to ~ 24 kpc. There is evidence for substantial color substructure among the metal-rich GCs. The metal-poor GCs have typical sizes ~ 0.4 pc larger than the metal-rich GCs out to large galactocentric distances (~> 20 kpc), favoring an intrinsic explanation for the size difference rather than projection effects. There is no clear relation between half-light radius and galactocentric distance beyond ~ 15 kpc, suggesting that the sizes of GCs are not generically set by tidal limitation. Finally, we identify ~ 20 candidate ultra-compact dwarfs that extend down to surprisingly faint absolute magnitudes (M_z ~ -8.5), and may bridge the gap between this class and "extended clusters" in the Local Group. Three of the brighter candidates have published radial velocities and can be confirmed as bona fide ultra-compact dwarfs; follow-up spectroscopy will determine the nature of the remainder of the candidates.Comment: ApJ in press. For redacted long table 1, see: http://www.pa.msu.edu/~strader/4649/table.te

Phenylcyanamidocopper(I) and Silver(I) Complexes: Synthetic and Structural Studies

Phenylcyanamidocopper(I) and silver(I) complexes of the type, [{M(PPh3)2L}2] (M = Cu, L = 4-NO2pcyd or 4-Me2Npcyd; M = Ag, L = 4-Me2Npcyd), [Cu(PPh3)3L] (L = pcyd or 4-NO2-pcyd), [Ag-(PPh3)3L] (L = pcyd, 2-Clpcyd, 4-Clpcyd, 4-Brpcyd, 4-MeOpcyd, 4-NO2pcyd or 4-Me2Npcyd), [Ag(Me2phen)(2-Clpcyd)] (Me2phen = 2,9-dimethyl-1,10-phenanthroline) and [Ag(dppm)(4-Brpcyd)] (dppm = bis(diphenylphosphino)methane) have been synthesised and characterised and the crystal structures of four of the complexes determined. For both [{Cu(PPh3)2(4-Me2Npcyd)}2] ⋅ CH2Cl2 and [{Ag(PPh3)2(4-Me2Npcyd)}2], the cyanamide ligands bridge the metal atoms in a μ-1,3-fashion through the cyano and amido nitrogens. Each metal atom has a distorted tetrahedral geometry, being bound to two triphenylphosphine phosphorus atoms and two nitro-gen atoms from 4-Me2Npcyd ligands to give a \u27P2N2\u27 coordination sphere. In the case of the Cu complex the dimer is centrosymmetric but for the Ag complex the metal atoms are not equivalent. The complexes, [Ag(PPh3)3(4-Brpcyd)] and [Ag(PPh3)3(4-Me-Opcyd)], are discrete monomers, in which each of the Ag atoms adopts a distorted tetrahedral geometry, being bound to three triphenylphosphine phosphorus atoms and one phenylcyanamide ligand binding in a terminal fashion through the cyano nitrogen

Spectroscopy of Globular Clusters in M81

We present moderate-resolution spectroscopy of globular clusters (GCs) around the Sa/Sb spiral galaxy M81 (NGC 3031). Sixteen candidate clusters were observed with the Low Resolution Imaging Spectrograph on the Keck I telescope. All are confirmed as bona fide GCs, although one of the clusters appears to have been undergoing a transient event during our observations. In general, the M81 globular cluster system (GCS) is found to be very similar to the Milky Way (MW) and M31 systems, both chemically and kinematically. A kinematic analysis of the velocities of 44 M81 GCS, (the 16 presented here and 28 from previous work) strongly suggests that the red, metal-rich clusters are rotating in the same sense as the gas in the disk of M81. The blue, metal-poor clusters have halo-like kinematics, showing no evidence for rotation. The kinematics of clusters whose projected galactocentric radii lie between 4 and 8 kpc suggest that they are rotating much more than those which lie outside these bounds. We suggest that these rotating, intermediate-distance clusters are analogous to the kinematic sub-population in the metal-rich, disk GCs observed in the MW and we present evidence for the existence of a similar sub-population in the metal-rich clusters of M31. With one exception, all of the M81 clusters in our sample have ages that are consistent with MW and M31 GCs. One cluster may be as young as a few Gyrs. The correlations between absorption-line indices established for MW and M31 GCs also hold in the M81 cluster system, at least at the upper end of the metallicity distribution (which our sample probes). On the whole, the mean metallicity of the M81 GCS is similar to the metallicity of the MW and M31 GCSs. The projected mass of M81 is similar to the masses of the MW and M31. Its mass profile indicates the presence of a dark matter halo.Comment: 35 pages, including 11 figures and 9 tables. Accepted for publication in the Astronomical Journa

Remote timed up and go evaluation from activities of daily living reveals changing mobility after surgery

Background: Mobility impairment is common in older adults and negatively influences the quality of life. Mobility level may change rapidly following surgery or hospitalization in the elderly. The timed up and go (TUG) is a simple, frequently used clinical test for functional mobility; however, TUG requires supervision from a trained clinician, resulting in infrequent assessments. Additionally, assessment by TUG in clinic settings may not be completely representative of the individual's mobility in their home environment. Objective: In this paper, we introduce a method to estimate TUG from activities detected in free-living, enabling continuous remote mobility monitoring without expert supervision. The method is used to monitor changes in mobility following total hip arthroplasty (THA). Methods: Community-living elderly (n = 239, 65-91 years) performed a standardized TUG in a laboratory and wore a wearable pendant device that recorded accelerometer and barometric sensor data for at least three days. Activities of daily living (ADLs), including walks and sit-to-stand transitions, and their related mobility features were extracted and used to develop a regularized linear model for remote TUG test estimation. Changes in the remote TUG were evaluated in orthopaedic patients (n = 15, 55-75 years), during 12-weeks period following THA. Main results: In leave-one-out-cross-validation (LOOCV), a strong correlation (p = 0.70) was observed between the new remote TUG and standardized TUG times. Test-retest reliability of 3-days estimates was high (ICC = 0.94). Compared to week 2 post-THA, remote TUG was significantly improved at week 6 (11.7 +/- 3.9 s versus 8.0 +/- 1.8 s,p &lt;0.001), with no further change at 12-weeks (8.1 +/- 3.9s, p = 0.37). Significance: Remote TUG can be estimated in older adults using 3-days of ADLs data recorded using a wearable pendant. Remote TUG has discriminatory potential for identifying frail elderly and may provide a convenient way to monitor changes in mobility in unsupervised settings.</p

Keck Spectroscopy of Candidate Proto-globular Clusters in NGC 1275

Keck spectroscopy of 5 proto-globular cluster candidates in NGC 1275 has been combined with HST WFPC2 photometry to explore the nature and origin of these objects and discriminate between merger and cooling flow scenarios for globular cluster formation. The objects we have studied are not HII regions, but rather star clusters, yet their integrated spectral properties do not resemble young or intermediate age Magellanic Cloud clusters or Milky Way open clusters. The clusters' Balmer absorption appears to be too strong to be consistent with any of the standard Bruzual & Charlot evolutionary models at any metallicity. If these models are adopted, an IMF which is skewed to high masses provides a better fit to the data. A truncated IMF with a mass range of 2-3 Mo reproduces the observed Balmer equivalent widths and colors at about 450 Myr. Formation in a continuous cooling flow appears to be ruled out since the age of the clusters is much larger than the cooling time, the spatial scale of the clusters is much smaller than the cooling flow radius, and the deduced star formation rate in the cooling flow favors a steep rather than a flat IMF. A merger would have to produce clusters only in the central few kpc, presumably from gas in the merging galaxies which was channeled rapidly to the center. Widespread shocks in merging galaxies cannot have produced these clusters. If these objects are confirmed to have a relatively flat, or truncated, IMF it is unclear whether or not they will evolve into objects we would regard as bona fide globular clusters.Comment: 30 pages (AAS two column style, including 9 tables and 7 figures) to appear in the AJ (August issue), also available at http://www.ucolick.org/~mkissler/Sages/sages.html (with a full resolution Fig.1) Revised Version: previous posted version was an uncorrect ealier iteration, parts of the text, tables and figures changed. The overall conclusions remain unchange